Test Quick Guide

HIV is a virus that attacks the immune system. As an HIV infection progresses, it increases the risk of cancer and life-threatening infections. In the United States, HIV is primarily spread through sex or sharing of needles with a person infected with HIV. Since HIV does not always present symptoms, it’s possible to have the virus and not be aware of it. About one in eight people in the U.S. don’t know that they have HIV, according to HIV.gov.

The Centers for Disease Control (CDC) recommends that everyone get tested at least once for HIV between the ages of 13 and 64. If you are at risk of HIV, it’s recommended that you get tested more regularly.

At-home HIV testing checks the blood or oral fluid for antigens and/or antibodies that are produced in response to the virus. At-home HIV testing is a form of screening that requires follow-up testing if test results are positive.

The Best At-Home HIV Tests Compared

Quest HIV Test

Best Overall
Type

Self-collection

Test for
  • HIV type 1 antibodies HIV type 2 antibodies
Results in

20 to 40 minutes

Insurance Accepted?

No

Who should use it

Sexually active adults who would like to test for HIV at home and don't need a follow-up consultation

Everlywell HIV Test

Best for Physician Follow-Up
Type

Self-collection

Test for
  • HIV type 1 antibodies
  • HIV type 2 antibodies
  • HIV p24 antigen
Results in

Within a few days

Insurance Accepted?

Yes

Who should use it

Sexually active adults who would like a physician follow-up if they test positive.

LetsGetChecked Standard 5

Best Panel Test That Includes HIV
Type

Self-collection

Test for
  • HIV type 1 antibodies
  • HIV type 2 antibodies
  • HIV p24 antigen
  • Chlamydia
  • Gonorrhea
  • Syphilis
  • Trichomoniasis
Results in

2 to 5 days

Insurance Accepted?

Yes

Who should use it

Sexually active adults who want to test for multiple STDs, including HIV.

myLAB Box HIV Home Test

Fastest Blood Test Results
Type

Self-collection

Test for
  • HIV type 1 antibodies
  • HIV type 2 antibodies
  • HIV p24 antigen
Results in

2 to 5 days

Insurance Accepted?

Yes

Who should use it

Sexually active adults looking to quickly determine if they may have HIV.

About At-Home HIV Tests

Purpose of at-home HIV tests

The purpose of at-home HIV testing is to quickly and easily determine if you may have HIV. If you get a positive result on an at-home HIV test, the CDC says you should get confirmatory testing in a medical laboratory as soon as possible.

What do the tests measure?

At-home HIV tests don’t look for the virus itself. Instead, they look for either antibodies alone or both antigens and antibodies. If these substances are detected, the test returns a positive result for HIV.

Antibodies are produced by the body in response to HIV infection. At-home tests that look for antibodies alone detect these substances in the blood or oral fluid. It can take several weeks after an HIV infection occurs for the body to produce antibodies, so it’s best to wait to take these tests until 12 weeks after you think you may have gotten infected.

Antigens are substances that the body recognizes as foreign and that activate an immune response. Testing for both antigens and antibodies at home requires taking a blood sample from a fingerstick. Because antigens appear before the body produces antibodies, HIV tests that look for both antigens and antibodies can detect an HIV infection within only 2 to 4 weeks of becoming infected.

How do at-home HIV tests work?

At-home HIV test kits include everything you need to collect a blood sample yourself and then send it back to a laboratory for testing. Kits will come with lancets to prick your finger and blood cards to collect the sample. You’ll then use the included shipping envelope to return your sample to the laboratory for testing. In most cases, you’ll be notified within a few business days that your results are available to view online.

Since at-home HIV test kits use only a nominal amount of blood, you don’t need to do much to prepare for your test beyond making sure to wash and sterilize the finger you’ll be using — generally a middle finger. You may also want to drink extra water beforehand to help with blood flow.

Which at-home HIV test should you choose?

While most at-home HIV tests look for both antibodies and the p24 antigen, some test kits also include physician follow-up or testing for additional STDs. When choosing a test kit, consider the price as well as reliability. You should look for a kit that uses a Clinical Laboratory Improvement Amendments (CLIA) certified lab to ensure it’s a high quality lab.

Benefits and Downsides of At-Home HIV Tests

At-home testing is not the same as getting tested in a medical office or lab. While there are many benefits to at-home HIV testing, you should also weigh the downsides before deciding which type of testing is right for you.

Benefits of at-home HIV testing include:

  • Convenience: You can do the test on your own time and without having to set up an appointment or travel to a medical facility.
  • Simplicity: Test kits are designed to make the process straightforward and easy to do in your own home.
  • Transparent pricing: Because you do the sample collection yourself, there are no copays or unexpected technician fees for at-home tests.

Downsides of at-home HIV testing include:

  • Confirmatory tests needed: Although generally accurate, at-home tests are not the final word. Test results, especially for HIV-positive results, need to be confirmed with an additional laboratory test.
  • Potential for errors in sample collection: While kits offer detailed instructions, the safeguards that exist to prevent errors and contamination in a specialized lab are not present in your home environment.
  • Results without a doctor’s guidance: With an at-home test, you won’t have your doctor immediately on hand to explain what the results mean for your health.
  • Varying test quality: Not all tests are created equal, and some tests may be more likely to return inaccurate results.
  • Not covered by insurance: You typically have to pay for at-home tests out-of-pocket and without insurance coverage.
  • Not available in all states: Regulatory requirements limit the availability of some types of at-home tests in certain U.S. states.

The Best At-Home HIV Tests

There are many different types of at-home HIV tests available, so it’s important to consider what type of HIV testing you’re looking for and at what price point before choosing. The following sections provide information about top picks for at-home HIV testing:

Methodology

At-home HIV tests were reviewed based on value, convenience, and availability of tests. These overall factors are based on data including price, insurance acceptance, comprehensiveness of tests, and how quickly you can get results and speak to a doctor. HIV test selections have been screened by Testing.com’s Medical Review Board.

Best Overall

Quest

Q
At-Home HIV Test
Price
$45
Type

Self-collection

Sample

Oral swab

Results timeline

20 to 40 minutes

Tests for
  • HIV type 1 antibodies HIV type 2 antibodies
Accuracy

Accepts insurance

No

Physician follow up

No

Prescriptions offered

No

Quest's easy-to-administer HIV test consists of an oral swab intended for home collection. The test checks for the presence of HIV-1 and HIV-2 by checking for antibodies in your oral fluid. These antibodies first appear during the three-month "window period" after an initial HIV infection. For the most accurate results, wait until at least three months have elapsed since your suspected exposure to HIV.

The test displays one line next to the C and no line next to the T if the results are negative. If any line — even a faint one — is displayed next to the T, you may have HIV and should contact your doctor for additional testing. You should refrain from eating, drinking, or using oral care products up to 30 minutes prior to taking the test. Your results should show 20 to 40 minutes after the sample has been collected.

This at-home test does not require you to ship the sample to a lab for analysis, so your results are confidential. Pre-test and post-test booklets are included in your packet. If you test positive, you can request a free call from Quest's care coordination team. Anyone 18 years or older is eligible, though the test is not permitted in Alaska, Arizona, or Hawaii.

WHAT’S GREAT?
  • Non-invasive test only requires an oral swab
  • Results available in less than an hour
  • No lab analysis needed
WHAT’S NOT SO GREAT?
  • Insurance not accepted for payment
  • Fasting required prior to test
  • Additional testing needed for those who test positive
Best for Physician Follow-Up

Everlywell

E
At-Home HIV Test
Price
$49, or $25 with membership
Type

Self-collection

Sample

Finger prick

Results timeline

Within a few days

Tests for
  • HIV type 1 antibodies
  • HIV type 2 antibodies
  • HIV p24 antigen
Accuracy

Testing is done by a CLIA approved lab

Accepts insurance

Yes

Physician follow up

Yes

Prescriptions offered

No

The Everywell at-home HIV test looks for both antibodies and antigens using a finger prick test. The high sensitivity of the fourth-generation technique used enables the test to detect HIV 18 to 90 days after exposure with 99% accuracy.

The test kits can be ordered from Everywell’s website to be delivered in discreet packaging. Once you register your kit online, you’ll be walked through how to collect your sample with a few drops of blood from a finger prick. You can then return your sample in the included mailing envelope using the prepaid shipping label. You’ll be notified when your results are ready to be viewed on Everywell’s secure, online platform, which usually takes around five days.

If your test comes back positive, a physician from Everywell’s network will reach out to help you determine the next steps to take.

While tests cost $49, you can get them for nearly 50% off if you sign up for the company’s membership plan called Control.

Users say it’s convenient to test with Everlywell’s kit with simple and clear directions. Most are able to finish the test in five minutes or less without any help, and results are returned quickly. However, some users complain of false positive results, which require a doctor follow-up.

WHAT’S GREAT?
  • Tests for antibodies and antigens
  • 99% accurate
  • Physician follow-up if you test positive
WHAT’S NOT SO GREAT?
  • Timeframe to get results may vary
  • Does not provide medication if you test positive
  • Does not accept insurance
Best Panel Test That Includes HIV

LetsGetChecked

LGC
At-Home HIV Test
Price
Type

Self-collection

Sample

Finger prick and urine sample

Results timeline

2 to 5 days

Tests for
  • HIV type 1 antibodies
  • HIV type 2 antibodies
  • HIV p24 antigen
  • Chlamydia
  • Gonorrhea
  • Syphilis
  • Trichomoniasis
Accuracy

Testing is done by a CAP and CLIA certified lab

Accepts insurance

Yes

Physician follow up

Yes

Prescriptions offered

No

If you’d like to get tested for more than HIV, LetsGetChecked’s Standard 5 test is the one for you. In addition to testing for HIV with an antibody and antigen test, the Standard 5 kit also screens for chlamydia, gonorrhea, syphilis and trichomoniasis, the STDs most commonly tested for by physicians.

The test kit includes a set of instructions, urine sample tube, urine collection cup, papett, four sterile lancets, blood collection tube, band-aids, alcohol wipes, band-aids, gauze, and a return envelope.

Please contact UPS to arrange a pickup before you collect your sample. You should collect your sample on the same day as the pickup is scheduled for. Visit the UPS pickup scheduling page or call 1-800-742-5877 to schedule a pickup to return your sample. You’ll be asked to provide some information including your tracking number, address, and pickup day and time. Please keep your tracking number to help you monitor your package.

There’s an online video to walk you through using your kit. You must collect your sample before 10 a.m. on Monday, Tuesday, Wednesday or Thursday and return it the same day.

If you test positive for any of STDs or HIV, you’ll receive clinical guidance. Treatment is available if you test positive for chlamydia or trichomoniasis.

People who have used LetsGetChecked’s STD panel say the test arrived quickly, it was easy to take the test in just a few minutes, and they got their results the same week. They found the testing procedure overall very simple to follow and the portal easy to use.

While this is a more comprehensive test, it’s also more expensive at $149. However, you can get 25% off with your exclusive Testing.com discount code. Use code TESTING25 at checkout.

WHAT’S GREAT?
  • Tests for antibodies and antigens
  • Over 99.99% accuracy
  • Free physician follow-up if you test positive
WHAT’S NOT SO GREAT?
  • More expensive than other options
  • More stringent collection procedure
  • Doesn’t accept insurance

Why is LetsGetChecked’s at-home HIV test the best panel?

LetsGetChecked’s test will tell you whether you test positive for HIV and four other STDs.

Who should use LetsGetChecked’s at-home HIV test?

Sexually active adults who want to test for multiple STDs, including HIV.

Fastest Blood Test Results

myLAB Box

MLB
At-Home HIV Test
Price
Type

Self-collection

Sample

Finger prick

Results timeline

2 to 5 days

Tests for
  • HIV type 1 antibodies
  • HIV type 2 antibodies
  • HIV p24 antigen
Accuracy

Testing is done by a CAP and CLIA certified lab

Accepts insurance

Yes

Physician follow up

Yes

Prescriptions offered

No

The HIV Home Test from myLAB Box offers fast delivery and quick results. You can order your kit online for delivery within two to five days. Collecting your sample with a quick finger prick takes only five minutes, then you just need to return it in the prepaid shipping envelope, which will send the sample directly to a CLIA-accredited lab for testing.

It should take only two to five days for the lab to analyze your sample. Once your results are available, you can view them online through myLAB Box’s secure portal. If you test positive for HIV, you can get free post-test telemedicine counseling by emailing myLABbox.

Reviewers say MyLAB Box’s test is discreet, easy to use, simple, and quick with clear results. They appreciate that it’s cost effective with quick results. However, some say they’d prefer to get value range results instead of a negative or positive.

While kits cost $79 normally, you can subscribe for regular testing to save 15%.

WHAT’S GREAT?
  • Tests for antibodies and antigens
  • Results in as little as 2 business days
  • Free physician follow-up if you test positive
WHAT’S NOT SO GREAT?
  • More expensive than other options
  • Currently unavailable in New York state
  • Doesn’t accept insurance

Interpreting At-Home Test Results

Generally, results from at-home HIV testing show whether the substance measured by the test was detected in the sample. If the substance was detected, this is reported as a positive test result.

Talking to your doctor is the best way to understand what an HIV test result means for your health. Important considerations related to the results of at-home HIV testing include:

  • Positive tests require follow-up: A positive HIV result on an at-home test requires follow-up with a medical professional.
  • Tests don’t detect recent HIV exposure: Depending on the type of test, it can take days, weeks, or even months for an infected person to test positive. For this reason, a negative result does not rule out an HIV infection if the test is taken too soon after potential exposure.
  • Tests should not guide behavior: High-risk behavior should be avoided regardless of whether a test result is positive or negative.
  • Regular screening may be necessary: Age, gender, health history, and number of sexual partners can affect what to test for and how often. It’s important to talk to your doctor about how often to be tested for HIVs.
  • Testing may cause anxiety: Getting the results of at-home HIV testing can cause anxiety. Consider reaching out to your doctor, a mental health professional, or a support organization to get support for the emotional impacts of testing.

Sources

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